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Dose Response Studies Against Puromycin Sensitive Aminopepti
2023-11-17
Dose–Response Studies Against Puromycin–Sensitive Aminopeptidase (PSA). PSA is a ubiquitous metallopeptidase encoded by the NPEPPS gene with subcellular distribution in the cytosol and nucleus [49]. Comprising of a 919 amino Reversine sequence, it has a broad substrate specificity, and is responsib
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Phytoremediation technology is defined as the use of plants
2023-11-17
Phytoremediation technology is defined as the use of plants to remove contaminants from soils or to render them harmless, and is regarded as a cost-effective, environmental-friendly method for reclaiming soils contaminated by toxic metals (Lasat, 2002, Mahar et al., 2016, Marrugo-Negrete et al., 201
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MT SGL encourages a individual feature selection based on th
2023-11-17
MT-SGL encourages (a) individual feature selection based on the utility of the features across all tasks with ℓ2,1-norm and (b) task specific group selection based on the utility of the group with G2,1-norm, i.e., fostamatinib synthesis regions of interest (ROI) for that task. Unlike basic SGL for
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Carmustine Medium spiny neurons MSNs in the striatum
2023-11-17
Medium spiny neurons (MSNs) in the striatum start from a deeply hyperpolarized resting membrane potential, slowly depolarize and show a delayed start of firing during a current injection (Kawaguchi, 1993, Nisenbaum and Wilson, 1995, Planert et al., 2013). The firing pattern during the current inject
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However cancer and fibrotic diseases are the most extensivel
2023-11-17
However, cancer and fibrotic diseases are the most extensively studied disease states. ATX is connected to various cancers because it can stimulate chemokinesis and chemotaxis in melanoma cells. Upregulated ATX methysergide synthesis has been reported in breast cancer,, prostate cancer, thyroid ca
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br Introduction Rhamdia quelen jundi Silurifomes Heptapterid
2023-11-16
Introduction Rhamdia quelen (jundiá, Silurifomes, Heptapteridae) is a neotropical catfish widely distributed in Central and South America (Silfvergrip, 1996). This species shows high potential for the aquaculture industry, due to an elevated growth rate, good carcass yield, and easy reproduction
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The most likely explanation for the species
2023-11-16
The most likely explanation for the species differences in aromatase distribution and the unique Oseltamivir distribution in humans is the unique location, size and highly elaborate organization of the human aromatase gene (e.g. Bulun et al., 2003). The human Cyp19 is a large gene located on chromo
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To elucidate whether membrane fluidity changes could
2023-11-16
To elucidate whether membrane fluidity changes could impact on signaling pathways, we examined the effects of Rh2 on the activation of Akt, a lipid raft-associated protein kinase, which promotes cell survival and blocks the apoptotic pathways. Upon pretreatment with 5 mM MβCD and in the absence of R
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In addition to attracting immune
2023-11-16
In addition to attracting immune cells to the site of injury, ROS also participate in proliferative responses during compensatory proliferation and regeneration. In Xenopus tadpoles, tail amputation induces sustained production of ROS over the span of regeneration, and decreasing ROS levels, especia
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Introduction Antimicrobial resistance is a growing health th
2023-11-16
Introduction Antimicrobial resistance is a growing health threat worldwide that has been associated with incorrect prescription and overuse of filgotinib [1]. Considering that physicians play a central role in antibiotic usage, a better understanding of their prescribing behaviours and their knowle
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br Introduction Quenchbody Q body immunoassay is a
2023-11-16
Introduction Quenchbody (Q-body) immunoassay is a novel biosensing technology that uses the quenching of fluorescence by intrinsic tryptophan (Trp) residues in antibody variable regions when dye(s) are conjugated to an antibody or antibody fragments in appropriate position, and de-quenching while
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AMPK is a central regulator of cell growth migration
2023-11-16
AMPK is a central regulator of cell growth, migration, metabolism, autophagy, and cell polarity [20], [21], [22], [23]. It is highly conserved in eukaryotes and functions as the primary sensor of intracellular adenosine nucleotides [24]. When intracellular ATP levels decrease, AMPK is activated to g
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A previous study showed that
2023-11-16
A previous study showed that miR-200c is involved in glucose-mediated pathological processes (Zhang, Guan, & Jin, 2017). Glucose metabolism is critical for the growth and proliferation of both normal amantadine hcl and cancer cells, and reprogramming glucose metabolism now has been considered as a
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Secondly as pointed out by
2023-11-16
Secondly, as pointed out by Sulentic and Kaminski in their recent paper [90], most of the AhR literature to date has focused on mouse AhR. Although both mouse and human AhR are interchangeable in many in vitro systems, the in vivo ligand binding affinity is drastically different between the two AhRs
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Voluminous literature about the neuroendocrine mechanism of
2023-11-16
Voluminous literature about the neuroendocrine mechanism of reproduction and energy regulation has emerged from studies involving mammalian species. The avian infundibular nucleus (equivalent structure to the mammalian arcuate nucleus) consists of two neuronal populations, one of which expresses neu
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